SBE13 is a potent and selective Plk1 inhibitor, with an IC50 of 200 pM; SBE13 poorly inhibits Plk2 (IC50>66 μM) or Plk3 (IC50=875 nM).

Product information

CAS Number: 775294-82-1

Molecular Weight: 442.94

Formula: C24H27ClN2O4

Synonym:

SBE-13

Chemical Name: ({4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl}methyl)[2-(3,4-dimethoxyphenyl)ethyl]amine

Smiles: COC1=CC=C(CCNCC2C=C(OC)C(=CC=2)OCC2=CN=C(Cl)C=C2)C=C1OC

InChiKey: XNPRQBVQOJZMMA-UHFFFAOYSA-N

InChi: InChI=1S/C24H27ClN2O4/c1-28-20-7-4-17(12-22(20)29-2)10-11-26-14-18-5-8-21(23(13-18)30-3)31-16-19-6-9-24(25)27-15-19/h4-9,12-13,15,26H,10-11,14,16H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

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